How much refrigerant does a Mercedes-Benz S Class A/C system hold?

The 2016 to 2017 Mercedes-Benz S Class (6 Cyl. 3.0 Eng. S550e; Gas/Electric) holds 25.6 oz of R-134a as a complete system charge. That is the amount for an empty, evacuated system, not for a top-off.

Can I put R-134a in a car that uses R-1234yf?

No. The two use different service fittings on purpose and different oils. Charging the wrong refrigerant can damage the compressor and is illegal in the US under EPA rules.

Can I recharge the A/C myself?

A DIY can with a gauge can top off a slightly low R-134a system. If the system is empty it has a leak, and adding refrigerant without fixing it wastes the can. A full charge needs the system evacuated and weighed in, which is a shop job.

Mercedes-Benz S Class A/C refrigerant type and capacity

GarageDex's A/C data shows the 2016 to 2017 Mercedes-Benz S Class (6 Cyl. 3.0 Eng. S550e; Gas/Electric) uses 25.6 oz of R-134a refrigerant with PAG-46 compressor oil.

Shop R-134a Match the type on your under-hood decal

Key takeaways

2016 to 2017 Mercedes-Benz S Class: 25.6 oz of R-134a, PAG-46 oil, see the under-hood decal for the rest.
The charge is a full-system amount; a top-off adds far less.
Do not mix refrigerant types or oils.
A system that is empty has a leak - fix it before charging.

Mercedes-Benz S Class A/C refrigerant and oil by year
Years	Engine	Refrigerant	Charge	Compressor oil
2016 to 2017	6 Cyl. 3.0 Eng. S550e; Gas/Electric	R-134a	25.6 oz	PAG-46
2016 to 2017	8 Cyl. 6.0 Eng. S600	R-134a	23.36 oz	PAG-46 4 oz
2014	12 Cyl. 5.5 Eng.	R-134a	34 oz	PAG-46 5.91 oz
2013	12 Cyl. 5.5 Eng.; w/o Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	6 Cyl. 3.0 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	6 Cyl. 3.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 4.6 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 4.6 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	8 Cyl. 5.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 5.5 Eng.; w/ 7SEU17C	R-134a	42 oz	PAG-46 3.72 oz
2012	8 Cyl. 6.2 Eng.	R-134a	38 oz	PAG-46 3.72 oz
2012	12 Cyl. 5.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	Cyl. 5.5 Eng.; w/o Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	6 Cyl. 3.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	6 Cyl. 3.5 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	8 Cyl. 4.6 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 4.6 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	8 Cyl. 5.5 Eng.; w/ 7SEU16C	R-134a	33 oz	PAG-46 4.06 oz
2012	8 Cyl. 5.5 Eng.; w/ 7SEU17C	R-134a	33 oz	PAG-46 4.74 oz
2012	8 Cyl. 6.2 Eng.	R-134a	33 oz	PAG-46 4.06 oz
2012	Cyl. 5.5 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	6 Cyl. 3.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	6 Cyl. 3.5 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	8 Cyl. 4.6 Eng.	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 5.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 5.5 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	8 Cyl. 6.2 Eng.	R-134a	38 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	6 Cyl. 3.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	6 Cyl. 3.5 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	8 Cyl. 4.6 Eng.	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 5.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 6.2 Eng.	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 6.3 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 6.3 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	Cyl. 5.5 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	8 Cyl. 4.6 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 5.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 5.5 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	8 Cyl. 6.3 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 6.3 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 4.6 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 5.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 5.5 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	8 Cyl. 6.3 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2012	8 Cyl. 6.3 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2012	Cyl. 6.0 Eng.	R-134a	41 oz	PAG-46 5.41 oz
2012	8 Cyl. 5.5 Eng.	R-134a	24 oz	PAG-46 4.05 oz
2012	Cyl. 6.0 Eng.	R-134a	37 oz	PAG-46 5.41 oz
2012	6 Cyl. 3.7 Eng.	R-134a	37 oz	PAG-46 5.41 oz
2012	8 Cyl. 4.3 Eng.	R-134a	37 oz	PAG-46 5.41 oz
2012	8 Cyl. 5.0 Eng.	R-134a	32 oz	PAG-46 4.73 oz
2012	8 Cyl. 5.5 Eng.	R-134a	24 oz	PAG-46 4.05 oz
2011	12 Cyl. 5.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2010	12 Cyl. 5.5 Eng.; w/ Rear AC	R-134a	42 oz	PAG-46 3.72 oz
2009	12 Cyl. 5.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2008	12 Cyl. 5.5 Eng.; w/o Rear AC	R-134a	38 oz	PAG-46 3.72 oz
2007	12 Cyl. 5.5 Eng.	R-134a	41 oz	PAG-46 5.41 oz
2006	12 Cyl. 5.5 Eng.	R-134a	37 oz	PAG-46 5.41 oz
2005	All Eng.; w/o Rear AC	R-134a	33.5 oz	PAG-46 6 oz
2005	All Eng.; w/o Rear AC	R-134a	37 oz	PAG-46 6 oz
2001 to 2004	All Eng.; w/o Rear AC	R-134a	33.5 oz	PAG-46 6 oz
2001 to 2004	All Eng.; w/ Rear AC	R-134a	37 oz	PAG-46 6 oz
1994 to 2000	All Eng.; w/o Rear AC	R-134a	39 oz	PAG-46 8 oz
1994 to 2000	All Eng.; w/ Rear AC	R-134a	41.5 oz	PAG-46 8.5 oz

Recharge supplies for your Mercedes-Benz S Class

Buy the refrigerant type shown for your year and confirm it against the under-hood decal. R-1234yf cans cost more and need a matching coupler.

R-134aR-134a recharge can with a gaugeShop cans Manifold gauge setReads high and low side pressure properlyShop gauges Leak detection kitFind the leak before you spend on refrigerantShop kits

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Source: Four Seasons - Compressor / System Refrigerant & Lubricant Specs. The under-hood A/C decal is the primary source for your exact car - it overrides any table. Charges assume a clean system with a new drier.