What gas does the 2025 Mercedes-Benz S-Class take?

The EPA rates every 2025 Mercedes-Benz S-Class engine on premium gasoline - Mercedes-Benz recommends or requires premium, and the label inside the fuel door says which.

Key takeaways

  • 5 EPA-certified configurations listed for the 2025 Mercedes-Benz S-Class.
  • Rated on premium: if the owner's manual says premium required, use premium; if it says recommended, regular works with some loss of power and economy.
  • None of the listed engines is flex-fuel, so do not use E85.
2025 Mercedes-Benz S-Class: every EPA-listed configuration
EngineTransmissionDriveRated fuelE85
3.0L 6-cylinder turbo hybrid mild hybrid9-speed automaticAWDpremium gasolineNo
3.0L 6-cylinder turbo plug-in hybrid9-speed automaticAWDpremium gasolineNo
4.0L 8-cylinder turbo hybrid mild hybrid9-speed automaticAWDpremium gasolineNo
4.0L 8-cylinder turbo plug-in hybrid9-speed automaticAWDpremium gasolineNo
6.0L 12-cylinder turbo9-speed automaticAWDpremium gasolineNo

Source: U.S. EPA / DOE fuel economy data (fueleconomy.gov). Each row is one certified configuration; a trim or option not sold in a configuration is not listed.

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